General Information

  • ID:  hor002968
  • Uniprot ID:  A0A7M7HPV7
  • Protein name:  SALMFamide
  • Gene name:  NA
  • Organism:  Strongylocentrotus purpuratus (Purple sea urchin)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Strongylocentrotus (genus), Strongylocentrotidae (family), Echinidea (infraorder), Camarodonta (order), Echinacea (superorder), Euechinoidea (subclass), Echinoidea (class), Echinozoa (superclass), Eleutherozoa, Echinodermata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  PHGGSAFVF
  • Length:  9
  • Propeptide:  MLFTMRVLVALALCLCFIAPSPVLSFTMPEEKFVENKMADVGEEGTGQNNINSIAKSLIREVFGAAEEREMEAENEAEDEAELSLSKRTTGSTRPQREIRARAQYAARRPPVTTRSKFTFGKRSSPTPVISRPLAEQLLEELQRNAEMSDDWRESDKLALLNDAALYDSLVDSHQVQKDAYSAFSFGKRGMSAFSFGKRAQPSFAFGKRGLMPSFAFGKRPHGGSAFVFGRRDWAPREQDFANAAEESGPYKRGDLAFAFGKREDQ
  • Signal peptide:  MLFTMRVLVALALCLCFIAPSPVLS
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A7M7HPV7-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002968_AF2.pdbhor002968_ESM.pdb

Physical Information

Mass: 106089 Formula: C44H59N11O11
Absent amino acids: CDEIKLMNQRTWY Common amino acids: FG
pI: 7.55 Basic residues: 1
Polar residues: 3 Hydrophobic residues: 4
Hydrophobicity: 57.78 Boman Index: 563
Half-Life: >20 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: ? Aliphatic Index 43.33
Instability Index: 1107.78 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  16272250
  • Title:  Molecular Characterisation of SALMFamide Neuropeptides in Sea Urchins